Men’s performance supplements often combine several herbs that are traditionally associated with libido, energy, circulation, and stamina. PowerUP is one of the more crowded formulas in this category, containing 14 active ingredients ranging from ginkgo and Asian ginseng to Tribulus, Epimedium, Muira Puama, and saw palmetto.
The formula looks broad, but the main scientific limitation is straightforward: the official website does not disclose individual ingredient amounts, and I could not identify a randomized clinical trial testing the finished PowerUP formula. In this PowerUp Max review, I looked at the ingredients, available research, safety, pricing, and whether the product’s male-performance claims are supported by evidence.
Quick Summary
| Product | PowerUP / PowerUp Max |
|---|---|
| Category | Men’s vitality and performance supplement |
| Form | Capsules |
| Serving | 2 capsules daily |
| Active ingredients | 14 |
| Individual doses | Not disclosed on official website |
| Product-specific clinical trial | None identified |
| Current price | $49–$79 per bottle, depending on package |
| Guarantee | 60 days |
| Editorial rating | 2.9/5 |
What Is PowerUp Max?
PowerUP is a dietary supplement marketed for men seeking support for vitality, energy, and overall well-being. The official website describes the formula as combining vitamins and traditional botanical extracts from different cultures. It recommends taking two capsules daily with water during meals.
The current formula contains 14 listed actives: vitamin E, niacin, hawthorn, Epimedium, damiana, Muira Puama, ginkgo biloba, Asian ginseng, Tribulus, Catuaba, saw palmetto, inosine, oat straw, and cayenne.
How Does PowerUp Work?
PowerUP takes a broad multi-mechanism approach. Several ingredients are traditionally associated with circulation and cardiovascular wellness, while others are marketed for libido, energy, or male vitality.
Asian ginseng and ginkgo have more human research than some of the lesser-known botanicals. Tribulus and Epimedium have also attracted research interest for sexual function, but the quality and relevance of that evidence varies.
Because the manufacturer does not disclose individual doses, however, it is impossible to determine whether the amounts in PowerUP match doses used in clinical studies.
PowerUp Ingredients
| Ingredient | Potential Role | Evidence |
|---|---|---|
| Vitamin E | Antioxidant and nutritional support | Not established as an ED treatment |
| Niacin | Energy metabolism | Some cardiovascular/ED research |
| Hawthorn | Cardiovascular support | Not established for ED |
| Epimedium | Traditional libido support | Mostly mechanistic/preclinical evidence |
| Damiana | Traditional sexual wellness | Limited human evidence |
| Muira Puama | Traditional libido support | Limited clinical evidence |
| Ginkgo Biloba | Circulation support | Mixed evidence |
| Asian Ginseng | Energy and sexual function | Some human evidence |
| Tribulus | Libido and sexual function | Low-certainty evidence |
| Catuaba | Traditional vitality support | Limited clinical evidence |
| Saw Palmetto | Prostate support | Not a proven performance ingredient |
| Inosine | Cellular energy metabolism | Limited relevance to male performance |
| Oat Straw | Traditional nervous-system support | Limited human evidence |
| Cayenne | Circulation/thermogenic support | Limited relevance to ED |
The ingredient list comes directly from the current official PowerUP page. Individual amounts are not provided there.
Asian Ginseng
Asian ginseng is one of the better-researched ingredients in the formula. NCCIH notes that some research suggests oral Asian ginseng may improve sexual function in people with erectile dysfunction, although most trials have been small and relatively short.
Study: Ginseng for erectile dysfunction — systematic review
This is useful ingredient-level evidence, but it does not prove that PowerUP improves erections because the product’s ginseng dose and extract specifications are not disclosed.
Tribulus Terrestris
Tribulus is frequently marketed as a natural testosterone booster. The evidence is more nuanced. A 2025 systematic review found that some clinical trials reported improved erectile function, but most studies did not show significant changes in androgen levels. The authors concluded that evidence for ED improvement remains low quality and that robust evidence for testosterone enhancement is lacking.
Study: Tribulus clinical trials systematic review
A newer meta-analysis of eight studies also found improvements in erectile-function scores compared with placebo but no significant difference in total testosterone.
Epimedium
Epimedium, commonly known as horny goat weed, contains icariin and is frequently marketed for male sexual performance. Laboratory research suggests that icariin can influence pathways involved in nitric oxide and PDE5 activity.
Study: Icariin and Epimedium review
However, much of the evidence remains mechanistic or preclinical. A 2026 review also concluded that clinical efficacy still requires confirmation in high-quality randomized trials.
Ginkgo Biloba
Ginkgo is often included in formulas marketed for circulation. However, NCCIH states that ginkgo has not been conclusively shown to be effective for the various conditions for which it is promoted.
There are some studies involving ginkgo-containing combinations and sexual function, but that evidence should not be interpreted as proof that ginkgo alone—or PowerUP—treats ED.
Other Botanicals
Damiana, Muira Puama, Catuaba, oat straw, hawthorn, and cayenne have histories of traditional use, but their clinical evidence for erectile dysfunction or testosterone enhancement is considerably weaker than the marketing around many male-performance products suggests.
Saw palmetto is better known for prostate and urinary-health products than for improving sexual performance. Inosine has biological roles in cellular metabolism, but that does not establish a meaningful performance benefit at the amount used in PowerUP.
Does PowerUp Really Improve Erectile Function?
There is not enough evidence to say that it does.
Several individual ingredients have been investigated for sexual function, especially Asian ginseng and Tribulus. However, the current evidence does not establish that the specific combination used in PowerUP improves erections.
The lack of individual doses is particularly important. A clinical trial using a standardized extract at a specific dose cannot be directly compared with a product when the product’s dose is unknown.
Can PowerUp Increase Testosterone?
I would not describe PowerUP as a clinically proven testosterone booster.
Tribulus has not produced robust testosterone results in clinical research, while Asian ginseng is not primarily established as a testosterone treatment. Epimedium has interesting laboratory mechanisms, but human evidence remains limited.
There is therefore insufficient evidence to claim that the finished PowerUP formula meaningfully raises testosterone.
Potential Benefits
- May provide general men’s wellness support.
- Contains several botanicals traditionally associated with libido.
- Asian ginseng has some human research involving sexual function.
- Tribulus has preliminary evidence involving erectile-function scores.
- Provides vitamin E and niacin as nutritional ingredients.
These should be considered potential ingredient-level benefits rather than clinically established effects of PowerUP.
Pros and Cons
Pros
- Broad 14-ingredient formula.
- Uses several botanicals with at least some human research.
- Simple two-capsule daily serving.
- Current ingredient list is publicly disclosed.
- 60-day money-back guarantee.
Cons
- Individual ingredient amounts are not disclosed.
- No product-specific clinical trial identified.
- Evidence for several botanicals is limited.
- Cannot compare the formula’s doses with clinical trials.
- Some ingredients have potential medication interactions.
- Large multi-ingredient formulas make it difficult to identify which component provides any benefit.
PowerUp vs. Prescription ED Treatment
| Factor | PowerUP | Prescription ED medication |
|---|---|---|
| Category | Dietary supplement | Medication |
| Clinical evidence | Ingredient-level | Drug-specific clinical trials |
| Individual dosing | Not disclosed | Standardized |
| FDA-approved ED treatment | No | Yes, for appropriate medications |
| On-demand use | Not established | Available for several ED medications |
NCCIH states that no complementary health approach has been definitively shown to be safe and effective for sexual enhancement or ED. Effective medical treatments are available through healthcare professionals.
Side Effects and Safety
The lack of individual doses makes the complete safety profile harder to assess. This matters because several ingredients can interact with medications.
Ginkgo may increase bleeding concerns, particularly with anticoagulant or antiplatelet drugs. Asian ginseng may affect blood glucose and blood clotting and can interact with medications. NCCIH also lists insomnia, allergic reactions, and rare liver problems among potential concerns.
Epimedium deserves particular caution because products containing icariin may have vascular effects. People taking nitrates or prescription ED medications should not assume that combining them with a multi-herbal supplement is safe.
Anyone with cardiovascular disease, high blood pressure, diabetes, bleeding disorders, or anyone taking prescription medication should discuss the complete formula with a healthcare professional before use.
FDA and Hidden-Ingredient Concerns
PowerUP is a dietary supplement, not an FDA-approved treatment for erectile dysfunction. The official website itself states that its claims have not been evaluated by the FDA.
This category also deserves additional caution. FDA and NCCIH warn that some sexual-enhancement products have been found to contain undeclared pharmaceutical ingredients. This does not mean PowerUP has been found to contain sildenafil, tadalafil, or another hidden drug. I found no FDA notification establishing that for this product.
It does mean that consumers should be particularly cautious with products making strong ED claims, especially when independent testing and detailed ingredient quantities are unavailable.
PowerUp Pricing and Packages
| Package | Price per Bottle | Total | Shipping |
|---|---|---|---|
| 2 bottles / 60 days | $79 | $158 | Additional shipping |
| 3 bottles / 90 days | $69 | $207 | Additional shipping |
| 6 bottles / 180 days | $49 | $294 | Free U.S. shipping |
These are the prices currently displayed on the official PowerUP website and can change. The site advertises a 60-day money-back guarantee. BuyGoods is identified as the retailer.
The six-bottle package requires a relatively large upfront purchase. Given the absence of product-specific clinical evidence, I would not consider buying six bottles simply to obtain the lower per-bottle price.
Customer Reviews
The official sales page currently does not provide a transparent, independently verifiable clinical evidence base for its product claims. Some third-party pages publish large numbers of positive customer testimonials, but I would not use those testimonials as evidence of efficacy.
Customer experiences can be useful for identifying common complaints or tolerability issues, but they cannot establish that a supplement improves testosterone or treats ED.
Who Might Consider PowerUp?
- Adult men interested in a broad botanical wellness formula.
- Men who understand that the product has not been clinically tested as a finished formula.
- People who have reviewed the complete ingredient list with a healthcare professional when appropriate.
Who Should Avoid It or Seek Medical Advice First?
- Men with persistent or unexplained erectile dysfunction.
- Anyone taking nitrates or prescription ED medication.
- People using blood thinners or antiplatelet medication.
- People with cardiovascular disease or uncontrolled blood pressure.
- Anyone taking multiple prescription medications.
- Men expecting a clinically proven testosterone treatment.
FAQs
What is PowerUp Max?
PowerUP is a 14-ingredient dietary supplement marketed for men’s vitality, energy, and overall wellness.
How many ingredients are in PowerUP?
The current official website lists 14 active ingredients.
What are the ingredients in PowerUP?
The formula contains vitamin E, niacin, hawthorn, Epimedium, damiana, Muira Puama, ginkgo biloba, Asian ginseng, Tribulus, Catuaba, saw palmetto, inosine, oat straw, and cayenne.
Does PowerUP contain L-arginine?
No. L-arginine is not listed among the 14 active ingredients on the current official product page.
Does PowerUP contain L-citrulline?
No. L-citrulline is not listed on the current official product page.
Can PowerUP increase testosterone?
There is insufficient evidence to establish that the finished PowerUP formula increases testosterone.
Can PowerUP treat erectile dysfunction?
No. PowerUP has not been clinically established as an ED treatment.
How should PowerUP be taken?
The manufacturer recommends two capsules daily with water during meals.
Is PowerUP FDA approved?
No. It is marketed as a dietary supplement rather than an FDA-approved medication.
How much does PowerUP cost?
The current official site lists packages ranging from $49 to $79 per bottle, depending on the quantity purchased.
Final Verdict
PowerUP has an extensive ingredient list and includes several botanicals with legitimate research interest. Asian ginseng has some evidence involving sexual function, while Tribulus has shown potential improvements in erectile-function scores in some trials. Epimedium also has interesting biological mechanisms.
However, the formula’s biggest weakness is dose transparency. The official site identifies the 14 ingredients but does not provide their individual quantities. Without those amounts, I cannot determine whether PowerUP delivers clinically relevant doses or meaningfully compare it with published research.
There is also no identified randomized clinical trial testing the complete PowerUP formula. Therefore, claims about improving erections, increasing testosterone, or substantially improving male performance remain unproven at the finished-product level.
My verdict: PowerUP is a broad men’s wellness formula with some scientifically interesting ingredients, but insufficient evidence and poor dose transparency prevent me from considering it a clinically proven testosterone or erectile-performance supplement.
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