Introduction
Nugenix Total-T2 is a men’s dietary supplement marketed as a combination testosterone and nitric oxide formula. The current version contains eight listed active ingredients, including L-citrulline malate, Tesnor®, Tongkat Ali, elevATP®, boron, vitamin D, zinc, and S7®.
The formula is positioned for testosterone support, energy, strength, endurance, exercise performance, and nitric oxide production. Some ingredients have human clinical research, and Tesnor® has been tested in randomized controlled trials. However, those findings should not be treated as proof that the complete Total-T2 formula produces the same results.
Quick Summary Box
| Product | Nugenix Total-T2 |
|---|---|
| Product Type | Men’s testosterone-support dietary supplement |
| Primary Uses | Testosterone, energy, exercise performance, nitric oxide support |
| Serving Size | 3 capsules |
| Servings | 30 per bottle |
| Key Ingredients | L-citrulline malate, Tesnor®, elevATP®, Tongkat Ali, S7®, boron |
| Stimulants | Company states the formula contains no stimulants |
| Product-Specific RCT | Not identified |
| Current Listed Price | $67.99 promotional price; $79.99 regular price |
| Guarantee | 100% customer satisfaction guarantee advertised |
What Is Nugenix Total-T2?
Total-T2 is the newer version of Nugenix’s Total-T testosterone-support formula. The company says the reformulated product adds S7® to its previous testosterone-support approach in order to target nitric oxide production as well.
The current serving is three capsules and provides 20 mcg vitamin D, 1 mg zinc, 1,125 mg L-citrulline malate, 400 mg Tesnor®, 150 mg elevATP®, 150 mg Tongkat Ali extract, 25 mg S7®, and 10 mg boron.
That level of label disclosure is useful because it makes it possible to compare individual ingredients with published research.
How It Works
Total-T2 uses two primary approaches.
The testosterone-support side relies mainly on Tesnor®, Tongkat Ali, vitamin D, and boron. The nitric-oxide side centers on L-citrulline malate, with the company also positioning S7® as an NO-support ingredient.
L-citrulline is converted to L-arginine and can contribute to nitric oxide production. Human research has found that 1.5 g/day of L-citrulline improved erection hardness in men with mild erectile dysfunction in a small clinical study. Total-T2 provides 1.125 g of L-citrulline malate per serving, although the amount of actual L-citrulline within that malate preparation is not separately stated on the label.
Nugenix Total-T2 Key Ingredients
L-Citrulline Malate – 1,125 mg
L-citrulline is an amino acid involved in the nitric oxide pathway. It can increase arginine availability, which may support blood flow.
A small clinical trial involving 24 men with mild erectile dysfunction found that 1.5 g/day of L-citrulline improved erection hardness from mild to normal in 50% of participants compared with 8.3% during placebo.
Total-T2 provides 1,125 mg of L-citrulline malate 2:1, not 1,125 mg of pure L-citrulline. Therefore, the research dose should not be directly equated with the amount of free L-citrulline supplied by Total-T2.
Study: PubMed – L-citrulline and erection hardness
Tesnor® – 400 mg
Tesnor® is a proprietary combination of pomegranate peel and cocoa seed extracts. This is one of the more important ingredients in Total-T2 because the branded ingredient itself has been tested in human trials.
A randomized, double-blind, placebo-controlled study of 120 healthy men aged 36–55 evaluated 200 mg and 400 mg Tesnor® for 56 days. Both doses improved Aging Male Symptoms scores, while free and total testosterone also increased compared with baseline and placebo. The 400 mg group additionally showed improvements in hand-grip strength and mid-upper-arm circumference.
A separate trial in healthy men aged 21–35 also found increases in testosterone with 200 mg and 400 mg Tesnor®.
Total-T2 provides 400 mg Tesnor®, matching the higher dose used in these studies. That makes Tesnor® one of the better-supported ingredients in this particular formula.
Study: PubMed – Tesnor® randomized trial in men aged 36–55
Additional study: PubMed – Tesnor® testosterone study in healthy men
elevATP® – 150 mg
elevATP® combines ancient peat and apple extracts and is marketed for cellular energy and physical performance.
The manufacturer uses elevATP® as part of its energy and exercise-performance strategy. However, the evidence base is much narrower than for ingredients such as L-citrulline or Tongkat Ali, and there is no identified Total-T2 trial establishing that 150 mg of elevATP® produces a meaningful increase in testosterone.
Therefore, it is better characterized as a performance-support ingredient rather than a clinically established testosterone booster.
Tongkat Ali – 150 mg
Tongkat Ali, or Eurycoma longifolia, has been studied extensively for testosterone and male sexual health.
A systematic review and meta-analysis of clinical trials found a significant improvement in total testosterone among men taking Eurycoma longifolia, although the researchers emphasized that more research is needed before routine clinical use.
A six-month randomized controlled study in men with androgen deficiency of aging males used 200 mg/day of Eurycoma longifolia and examined testosterone and erectile function.
Total-T2 contains 150 mg of Tongkat Ali extract, so the dose differs from the 200 mg used in that trial. Extract standardization also matters when comparing products.
Study: PubMed – Tongkat Ali systematic review and meta-analysis
Additional study: PubMed – Tongkat Ali randomized clinical trial
S7® – 25 mg
S7® is a seven-plant blend containing green coffee extract, green tea extract, turmeric, sour cherry, blueberry, broccoli, and kale. Nugenix says it added S7® to support nitric oxide production.
The limitation is that the total blend weighs only 25 mg and the label does not provide individual quantities for its seven botanical components. That makes direct comparison with ingredient-specific clinical doses difficult.
The company also promotes an increase in nitric oxide within three hours. This is a manufacturer claim rather than evidence that Total-T2 produces a clinically meaningful improvement in erectile function or cardiovascular performance.
Boron – 10 mg
Boron is included at 10 mg per serving.
Older human research has investigated whether boron supplementation affects testosterone. A small randomized trial involving 19 male bodybuilders used 2.5 mg/day for seven weeks and measured testosterone, lean body mass, and strength.
That study is very small and old, and its findings should not be used as strong evidence that 10 mg boron will increase testosterone in typical adult men.
Study: PubMed – Boron, testosterone, lean body mass and strength
Vitamin D – 20 mcg
Total-T2 provides 20 mcg (800 IU) vitamin D3. Vitamin D is important for normal bone, immune, and metabolic function, but its role as a testosterone booster is uncertain.
A 2026 systematic review and meta-analysis of randomized trials found no clear or reproducible effect of vitamin D supplementation on total testosterone or androgen-bioavailability markers in adult men.
An earlier 2019 meta-analysis also found no significant effect of vitamin D supplementation on total testosterone or SHBG.
Study: PubMed – 2026 vitamin D and testosterone meta-analysis
Zinc – 1 mg
Total-T2 contains 1 mg zinc as zinc citrate. Zinc is essential for normal reproductive and metabolic function, but 1 mg is relatively modest compared with the adult recommended intake of 11 mg/day.
Zinc supplementation is most relevant when dietary intake is inadequate or deficiency exists. It should not automatically be considered a testosterone booster for men with normal zinc status.
Nugenix Total-T2 Benefits
Based on the formula and available research, Total-T2 may:
- Support testosterone levels through ingredients such as Tesnor® and Tongkat Ali.
- Promote nitric oxide production through L-citrulline.
- Support blood-flow-related exercise and sexual function.
- Enhance perceived energy and exercise performance, although product-specific evidence is limited.
- Provide vitamin D, zinc, and boron alongside the primary botanical ingredients.
These are potential benefits based on the formulation and ingredient evidence. They should not be interpreted as guaranteed changes in testosterone, muscle mass, libido, or sexual performance.
Nugenix Total-T2 Pros & Cons
Pros
- Fully disclosed active ingredient amounts.
- Contains 400 mg Tesnor®, matching the higher dose used in a human randomized trial.
- Includes 1,125 mg L-citrulline malate for nitric oxide support.
- Includes Tongkat Ali, which has human testosterone research.
- No conventional stimulant ingredients are marketed in the formula.
- Company publishes a 2025 certificate-of-analysis summary for the product.
Cons
- No identified randomized controlled trial testing the complete Total-T2 formula.
- Several proprietary ingredients are difficult to compare directly with clinical research.
- S7® contains seven botanical ingredients but does not disclose individual amounts.
- Tongkat Ali dose is lower than the 200 mg used in one notable clinical trial.
- Evidence for boron and vitamin D as testosterone boosters is limited or inconsistent.
- Marketing claims about rapid nitric oxide and testosterone effects are stronger than the product-specific evidence.
Comparison Table With Alternatives
| Product/Approach | Main Focus | Key Evidence Consideration | Format |
|---|---|---|---|
| Nugenix Total-T2 | Testosterone + nitric oxide | Strongest evidence is ingredient-level, especially Tesnor® and Tongkat Ali | 3 capsules/day |
| Tongkat Ali | Testosterone support | Human trials and meta-analysis available | Capsules |
| L-Citrulline | Nitric oxide/blood flow | Human research for vascular and mild ED outcomes | Powder/capsules |
| Prescription testosterone therapy | Clinically diagnosed hypogonadism | Extensive clinical evidence; requires medical evaluation | Prescription |
The main distinction is that Total-T2 combines testosterone-oriented ingredients with a relatively substantial nitric-oxide component. A single-ingredient supplement can make it easier to compare the dose with clinical studies, while prescription testosterone is a fundamentally different medical intervention used when hypogonadism has been properly diagnosed.
Customer Reviews
Nugenix currently advertises 9,800+ five-star reviews across its Total-T2 marketing pages. The displayed testimonials describe improvements in energy, strength, libido, and perceived performance. These are company-presented customer reports and should not be treated as clinical evidence.
Independent discussion is more mixed. Recent Reddit discussions include users reporting little or no noticeable change after using Total-T2, while others discuss specific ingredients such as L-citrulline and Tongkat Ali. These comments are anecdotal and cannot establish product effectiveness.
Who Should Use Nugenix Total-T2?
Total-T2 may be relevant to adult men who:
- Want a non-prescription testosterone-support supplement.
- Prefer a combination of testosterone and nitric-oxide ingredients.
- Want a fully disclosed supplement label.
- Are interested in L-citrulline for blood-flow support.
- Already maintain appropriate exercise, sleep, nutrition, and resistance-training habits.
It should be viewed as a dietary supplement rather than a treatment for diagnosed testosterone deficiency.
Who Should Avoid or Discuss It With a Clinician?
Men should discuss Total-T2 with a healthcare professional before use if they:
- Have been diagnosed with low testosterone or hypogonadism.
- Have cardiovascular disease or blood-pressure concerns.
- Take prescription medications.
- Use erectile-dysfunction medications or nitrate medications.
- Have liver or kidney disease.
- Are preparing for surgery.
- Have unexplained changes in libido, erectile function, energy, or mood.
Persistent symptoms associated with low testosterone deserve proper testing. Testosterone levels can fluctuate, and diagnosis generally requires appropriate clinical evaluation rather than relying on symptoms alone.
Side Effects & Safety
The current formula contains several ingredients with human safety data, but the combined Total-T2 formula has not been tested in a dedicated clinical trial.
L-citrulline: Human studies generally report good short-term tolerability, but it may affect blood pressure in some people and could interact with medications that lower blood pressure.
Tongkat Ali: Human trials have generally reported reasonable short-term tolerability, but long-term safety data remain more limited.
Tesnor®: The clinical trials of the branded ingredient reported favorable safety findings over 56 days, but this does not establish long-term safety for every user.
Boron: Total-T2 provides 10 mg. The NIH Office of Dietary Supplements notes that the U.S. National Academies has not established a formal Tolerable Upper Intake Level for boron, but excessive intake can be harmful and high supplemental doses should not be combined casually with other boron-containing products.
Vitamin D: The product provides 800 IU per serving. Total intake from other supplements should be considered.
Anyone taking prescription medication should review the complete formula with a physician or pharmacist before use.
Does Nugenix Total-T2 Really Increase Testosterone?
There is a meaningful distinction between the ingredients showing testosterone effects in studies and Total-T2 itself being clinically proven.
Tesnor® is the strongest example. A randomized, double-blind trial in men aged 36–55 found that both 200 mg and 400 mg doses improved free and total testosterone compared with placebo after 56 days. Total-T2 contains 400 mg.
Tongkat Ali also has a broader evidence base. A 2022 systematic review and meta-analysis of randomized clinical trials found an increase in total testosterone, although the authors said more research is necessary before routine clinical application.
At the same time, a 2023 systematic review of testosterone boosters found that most ingredients and products do not consistently increase total testosterone. The authors considered Eurycoma longifolia and Tesnor® among the ingredients that may have potential, while emphasizing the limitations of the evidence.
Therefore, it would be inaccurate to describe Total-T2 as clinically proven to raise testosterone in all men.
Pricing & Packages
Nugenix’s current product listings show Total-T2 at a regular price of $79.99 per bottle, with the main product page currently displaying a promotional price of $67.99 per bottle.
A separate current sales page displays different promotional package pricing, illustrating that offers can vary by page and promotion. One current offer shows one bottle at $69, two bottles at $58 each, and four bottles at $50 each. Subscription pricing is also advertised.
| Package | Displayed Price | Approx. Supply |
|---|---|---|
| 1 Bottle | About $67.99–$79.99 depending on offer | 30 days |
| 2 Bottles | Promotional offers vary | 60 days |
| 4 Bottles | Promotional offers vary | 120 days |
Nugenix also advertises a 100% customer satisfaction guarantee on its current Total-T2 sales material.
10 Frequently Asked Questions
1. What is Nugenix Total-T2?
Nugenix Total-T2 is a men’s dietary supplement designed to support testosterone, nitric oxide, energy, strength, and exercise performance.
2. What ingredients are in Total-T2?
The current formula contains vitamin D, zinc, L-citrulline malate, Tesnor®, elevATP®, Tongkat Ali, S7®, and boron.
3. How many Total-T2 capsules should be taken daily?
The current serving size is three capsules, with 30 servings in a 90-capsule bottle.
4. Does Total-T2 contain testosterone?
No. It is a dietary supplement intended to support the body’s testosterone production rather than providing testosterone itself.
5. Does Total-T2 increase testosterone?
Some ingredients, particularly Tesnor® and Tongkat Ali, have human research suggesting potential testosterone increases. However, the complete Total-T2 formula has not been established in a published randomized controlled trial.
6. How quickly does Total-T2 work?
Nugenix markets nitric oxide effects within three hours and testosterone-related results over subsequent weeks. These are manufacturer claims and should not be interpreted as guaranteed clinical outcomes.
7. Does Total-T2 help erectile function?
Its L-citrulline component has some human evidence for mild erectile dysfunction, but Total-T2 itself has not been clinically established as an erectile-dysfunction treatment.
8. Is Total-T2 a stimulant?
Nugenix describes the formula as containing no stimulants. However, S7® includes green coffee and green tea extracts, so people sensitive to botanical caffeine sources should review the current label carefully.
9. Can Total-T2 replace testosterone replacement therapy?
No. There is no evidence establishing Total-T2 as a replacement for medically prescribed testosterone therapy in men with confirmed hypogonadism.
10. How much does Nugenix Total-T2 cost?
The official site currently shows approximately $67.99 on promotion versus a $79.99 regular price, while other current promotional pages display different package prices.
Final Verdict
Nugenix Total-T2 has a more transparent formulation than many testosterone supplements. The label provides specific amounts for its eight active ingredients, and Tesnor® is particularly notable because the exact 400 mg dose in Total-T2 was used in a randomized controlled trial involving men aged 36–55. That study reported improvements in free and total testosterone as well as Aging Male Symptoms scores.
Tongkat Ali also has a meaningful human research base, including a systematic review and meta-analysis showing an increase in total testosterone across randomized clinical trials. L-citrulline provides a separate rationale for nitric-oxide and blood-flow support.
However, the evidence for Total-T2 itself remains limited. There is no identified randomized controlled trial showing that the complete eight-ingredient formula increases testosterone, muscle mass, energy, or sexual performance. The company’s claims about rapid nitric oxide production and broad performance benefits therefore need to be distinguished from independently established clinical outcomes.
The dose comparisons also matter. Total-T2 supplies 150 mg Tongkat Ali, while a notable clinical trial used 200 mg, and its 1,125 mg L-citrulline malate is not equivalent to 1,125 mg pure L-citrulline. The S7® blend is also not individually quantified.
Overall, Nugenix Total-T2 is best characterized as a multi-ingredient testosterone- and nitric-oxide-support supplement with some promising ingredient-level evidence. It should not be presented as a clinically proven treatment for low testosterone, hypogonadism, or erectile dysfunction.
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